{"id":58824,"date":"2023-11-24T14:42:44","date_gmt":"2023-11-24T14:42:44","guid":{"rendered":"https:\/\/leitat.org\/blog\/biosysmo\/"},"modified":"2025-02-24T21:04:32","modified_gmt":"2025-02-24T21:04:32","slug":"biosysmo","status":"publish","type":"post","link":"https:\/\/leitat.org\/en\/blog\/biosysmo\/","title":{"rendered":"BIOSYSMO"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"58824\" class=\"elementor elementor-58824 elementor-23677\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4698cb58 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4698cb58\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1d63a399\" data-id=\"1d63a399\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-598741a9 elementor-widget elementor-widget-text-editor\" data-id=\"598741a9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>BIOremediation systems exploiting SYnergieS for improved removal of Mixed POllutants.<\/em><\/p><p><strong>Website: <a href=\"https:\/\/www.biosysmo.eu\/\">biosysmo.eu<\/a><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-68b90c7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"68b90c7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8e80e95\" data-id=\"8e80e95\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6f33cde3 elementor-widget elementor-widget-text-editor\" data-id=\"6f33cde3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>ABSTRACT<\/strong><\/p><p>BIOSYSMO is a 48-month action that will develop a computationally-assisted framework for designing and optimizing synergistic biosystems combining the required pathways and traits to achieve the most efficient degradation and sequestration of pollutant mixtures. These biosystems will comprise combinations of bacteria, fungi and plants containing the natural or engineered pathways required for pollutants degradation and identified based on a computationally-assisted analysis.<\/p><p>BIOSYSMO will take advantage of the high natural microbial diversity by screening samples from polluted sites and locations affected by diffuse pollution to identify natural microorganisms already present and able to metabolize the target pollutants. The search will be expanded to microorganisms previously identified and characterized by applying data mining tools to genomic and metagenomic data available in public repositories.<\/p><p>The construction and optimization of synergistic biosystems will combine approaches based on 1) enhancing plantmicrobe (bacteria, fungi) interactions to achieving combinations with improved pollutant uptake and\/or degradation; 2) engineering bacteria, for improved degradation and bioaugmentation, and plants (poplar tree), for improved microbial colonization and pollutant uptake; 3) constructing artificial micro-structured consortia into aggregates and biofilms, containing all the required pathways for pollutant removal; and 4) applying bioelectrochemical systems (BES) as standalone or in hybrid systems. The different key players will be identified and combined to formulate innovative biosystems with the assistance of genome-scale metabolic (GEM) models for elucidating and simulating the key metabolic pathways.<\/p><p>The constructed biosystems will be applied in conventional (phytoremediation, biopile, bioaugmentation) and innovative (BES, hybrid BES-phytoremediation) bioremediation approaches optimized for the treatment of mixtures of pollutants in soil, sediments and water.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2c5be219 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2c5be219\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-30d4e8e4\" data-id=\"30d4e8e4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-23ee6b06 elementor-widget elementor-widget-text-editor\" data-id=\"23ee6b06\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Project Budget: <\/strong>5,355,138\u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-213bb0d3 elementor-widget elementor-widget-text-editor\" data-id=\"213bb0d3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Leitat Budget: <\/strong>469,540\u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-76cfe230\" data-id=\"76cfe230\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-228c44ba elementor-widget elementor-widget-text-editor\" data-id=\"228c44ba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Financial Framework: <\/strong>HORIZON EUROPE<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-63314675 elementor-widget elementor-widget-text-editor\" data-id=\"63314675\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contract number: <\/strong>101060211<strong><br \/><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-64908a0f\" data-id=\"64908a0f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-72a25806 elementor-widget elementor-widget-text-editor\" data-id=\"72a25806\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Start Date:<\/strong> 01\/09\/2022<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3fad4c2c elementor-widget elementor-widget-text-editor\" data-id=\"3fad4c2c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>End Date:<\/strong> 31\/08\/2026<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-05bac3c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"05bac3c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5731076\" data-id=\"5731076\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8a3573b elementor-widget elementor-widget-text-editor\" data-id=\"8a3573b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h6><strong>Leitat<\/strong><\/h6><p>Main role &amp; contribution in the project:<\/p><ul><li><p>Assess the (eco)toxicity of polluted and treated samples coming from the methods developed and tested in the WP \u201c<i>Application of biosystems for depollution of different pollutants and environmental matrices\u201d.<\/i><\/p><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-56106921 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"56106921\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9e6a531\" data-id=\"9e6a531\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-20952cdc elementor-widget elementor-widget-text-editor\" data-id=\"20952cdc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Partners:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c6f5329 elementor-widget elementor-widget-image\" data-id=\"c6f5329\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"200\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2-1024x256.png\" class=\"attachment-large size-large wp-image-53449\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2-1024x256.png 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2-300x75.png 300w, https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2-768x192.png 768w, https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2-1536x384.png 1536w, https:\/\/leitat.org\/wp-content\/uploads\/2023\/11\/Funded-by-the-European-Union-under-Grant-101083780.-Views-and-opinions-expressed-are-however-those-of-the-authors-only-and-do-not-necessarily-reflect-those-of-the-European-Union.-Neither-the-Eu-2.png 1584w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d8c697 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d8c697\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-56bba243\" data-id=\"56bba243\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-362436e2 elementor-widget elementor-widget-image\" data-id=\"362436e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"600\" height=\"401\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/03\/flag_yellow_low1-1.jpg\" class=\"attachment-large size-large wp-image-46769\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/03\/flag_yellow_low1-1.jpg 600w, https:\/\/leitat.org\/wp-content\/uploads\/2016\/03\/flag_yellow_low1-1-300x201.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-53b68e0b\" data-id=\"53b68e0b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-44dceb42 elementor-widget elementor-widget-text-editor\" data-id=\"44dceb42\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Funded by the European Union under the GA no 101060211. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or REA. Neither the European Union nor the granting authority can be held responsible for them.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>BIOremediation systems exploiting SYnergieS for improved removal of Mixed POllutants. Website: biosysmo.eu ABSTRACT BIOSYSMO is a 48-month action that will develop a computationally-assisted framework for designing and optimizing synergistic biosystems combining the required pathways and traits to achieve the most efficient degradation and sequestration of pollutant mixtures. These biosystems will comprise combinations of bacteria, fungi [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":53447,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[124],"tags":[112],"class_list":["post-58824","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-horizon-europe-en","tag-projects"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BIOSYSMO - Leitat Technological Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BIOSYSMO - Leitat Technological Center\" \/>\n<meta property=\"og:description\" content=\"BIOremediation systems exploiting SYnergieS for improved removal of Mixed POllutants. Website: biosysmo.eu ABSTRACT BIOSYSMO is a 48-month action that will develop a computationally-assisted framework for designing and optimizing synergistic biosystems combining the required pathways and traits to achieve the most efficient degradation and sequestration of pollutant mixtures. 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