{"id":59423,"date":"2018-06-01T12:44:38","date_gmt":"2018-06-01T12:44:38","guid":{"rendered":"https:\/\/leitat.org\/blog\/fitomatics\/"},"modified":"2025-02-24T20:50:28","modified_gmt":"2025-02-24T20:50:28","slug":"fitomatics","status":"publish","type":"post","link":"https:\/\/leitat.org\/en\/blog\/fitomatics\/","title":{"rendered":"FITOMATICS"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"59423\" class=\"elementor elementor-59423 elementor-13664\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4f7ad3c9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4f7ad3c9\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-16b80fd2\" data-id=\"16b80fd2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-412f4390 elementor-widget elementor-widget-heading\" data-id=\"412f4390\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">FITOMATICS<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6188f3ed elementor-widget elementor-widget-text-editor\" data-id=\"6188f3ed\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><span class=\"tlid-translation translation\"><span class=\"\" title=\"\">Production of volatile organic and antimicrobial compounds <\/span><span class=\"\" title=\"\">through biotechnological processes based on the use of endophytes and <\/span><span class=\"\" title=\"\">metabolic engineering<\/span><\/span><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2af60c82 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2af60c82\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-63e9eb14\" data-id=\"63e9eb14\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-29e0bb3 elementor-widget elementor-widget-text-editor\" data-id=\"29e0bb3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>ABSTRACT<\/strong><\/p><p><span class=\"tlid-translation translation\">The project aims to exploit the emerging strategy of the use of plant endophytes -an endosymbiotic group of microorganisms that colonize plants- as reservoirs of metabolic diversity for the production of new bioactive secondary metabolites interesting in the field of fragrances. Like plants, endophytes harbor a great metabolic diversity presenting some metabolic pathways of plants incorporated in their genome and new pathways specific to their metabolism. Unlike plants, endophytes present the regulatory genes of a specific metabolic pathway grouped in operons, under the control of a single promoter, thus facilitating the elucidation of synthetic routes. Therefore, endophytes have an enormous potential to produce new bioactive compounds of natural origin, without the need to extract these compounds directly from the plant. <\/span><\/p><p><span class=\"tlid-translation translation\">In addition, the alternative use of endophytes could alleviate serious problems such as overexploitation of plants, deforestation or loss of biodiversity. On the other hand, most of the compounds synthesized, both by plants and by endophytes, have very complex structures with multiple chiral centers, so the chemical synthesis of these compounds implies multiple stereoselective reactions, which result in obtaining racemic mixtures of compounds that must be separated to obtain the desired final product. This entails an increase in the cost of the products obtained by chemical synthesis and makes their commercialization a totally unfeasible process. In contrast, endophytes can serve as a basis to identify metabolic pathways for the synthesis of bioactive compounds, which can be transferred to heterologous hosts and thus facilitate the industrial production of the compounds of interest.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-17098751 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"17098751\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-720b5504\" data-id=\"720b5504\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4e517666 elementor-widget elementor-widget-text-editor\" data-id=\"4e517666\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Project Budget:<\/strong> 1.079.536,99 \u20ac<strong><br \/><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-259cf2fd elementor-widget elementor-widget-text-editor\" data-id=\"259cf2fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>LEITAT Budget: <\/strong>193.350,61 \u20ac<strong><br \/><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-78293ae\" data-id=\"78293ae\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-62066a58 elementor-widget elementor-widget-text-editor\" data-id=\"62066a58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Financial Framework: <\/strong>RTC<strong><br \/><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d84ed58 elementor-widget elementor-widget-text-editor\" data-id=\"3d84ed58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contract number: <\/strong>RTC-2017-6431-2<strong><br \/><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-3fb1363a\" data-id=\"3fb1363a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-93a2104 elementor-widget elementor-widget-text-editor\" data-id=\"93a2104\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Start Date:<\/strong> 01\/06\/2018<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-43d73b71 elementor-widget elementor-widget-text-editor\" data-id=\"43d73b71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>End Date:<\/strong> 31\/12\/2021<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-225933c4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"225933c4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-32def2f8\" data-id=\"32def2f8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7203e352 elementor-widget elementor-widget-text-editor\" data-id=\"7203e352\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Partners:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-584aada7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"584aada7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7c17916f\" data-id=\"7c17916f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-98dfa7f elementor-widget elementor-widget-image-gallery\" data-id=\"98dfa7f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-gallery.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-gallery\">\n\t\t\t<div id='gallery-1' class='gallery galleryid-59423 gallery-columns-4 gallery-size-full'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img fetchpriority=\"high\" width=\"2048\" height=\"850\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA.jpg\" class=\"attachment-full size-full\" alt=\"\" aria-describedby=\"gallery-1-50905\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA.jpg 2048w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA-300x125.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA-768x319.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA-1024x425.jpg 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/NEW_logo_GRUPO_CARINSA-1536x638.jpg 1536w\" sizes=\"(max-width: 2048px) 100vw, 2048px\" \/>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-50905'>\n\t\t\t\tCoordinator\n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"1123\" height=\"583\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/LOGO_CRAG_ENG.jpg\" class=\"attachment-full size-full\" alt=\"\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/LOGO_CRAG_ENG.jpg 1123w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/LOGO_CRAG_ENG-300x156.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/LOGO_CRAG_ENG-768x399.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/01\/LOGO_CRAG_ENG-1024x532.jpg 1024w\" sizes=\"(max-width: 1123px) 100vw, 1123px\" \/>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"200\" height=\"76\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/Leitat_ppt-200.png\" class=\"attachment-full size-full\" alt=\"\" decoding=\"async\" \/>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-33068e34 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"33068e34\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c695eb6\" data-id=\"c695eb6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68fbd3fb elementor-widget elementor-widget-text-editor\" data-id=\"68fbd3fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contact Manager:<\/strong> <a href=\"mailto:snieva@leitat.org\">S. Nieva<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5c3116eb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5c3116eb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-1b01d35b\" data-id=\"1b01d35b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-14882ae7 elementor-widget elementor-widget-image\" data-id=\"14882ae7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"155\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg\" class=\"attachment-large size-large wp-image-51091\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-300x58.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-768x149.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1536x298.jpg 1536w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cc83fba elementor-widget elementor-widget-image\" data-id=\"cc83fba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"535\" height=\"142\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/07\/LOGO_FEDER_es-670x300-1.png\" class=\"attachment-large size-large wp-image-55475\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/07\/LOGO_FEDER_es-670x300-1.png 535w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/07\/LOGO_FEDER_es-670x300-1-300x80.png 300w\" sizes=\"(max-width: 535px) 100vw, 535px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-66bc7433\" data-id=\"66bc7433\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3c3e416b elementor-widget elementor-widget-text-editor\" data-id=\"3c3e416b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Financiado por: FEDER\/Ministerio de Ciencia,Innovaci\u00f3n y Universidades \u2013 Agencia Estatal de Investigaci\u00f3n\/_Proyecto RTC-2017-6431-2<\/p><p>Objetivo Tem\u00e1tico del Programa Operativo: Promover el desarrollo tecnol\u00f3gico, la innovaci\u00f3n y una investigaci\u00f3n de calidad.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>FITOMATICS Production of volatile organic and antimicrobial compounds through biotechnological processes based on the use of endophytes and metabolic engineering ABSTRACT The project aims to exploit the emerging strategy of the use of plant endophytes -an endosymbiotic group of microorganisms that colonize plants- as reservoirs of metabolic diversity for the production of new bioactive secondary [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":50909,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[132],"tags":[112],"class_list":["post-59423","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-circular-economy-en","tag-projects"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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