{"id":59980,"date":"2014-10-01T10:51:28","date_gmt":"2014-10-01T10:51:28","guid":{"rendered":"https:\/\/leitat.org\/blog\/nano4derm\/"},"modified":"2025-02-24T20:34:18","modified_gmt":"2025-02-24T20:34:18","slug":"nano4derm","status":"publish","type":"post","link":"https:\/\/leitat.org\/en\/blog\/nano4derm\/","title":{"rendered":"NANO4DERM"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"59980\" class=\"elementor elementor-59980 elementor-8057\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dlevvcb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dlevvcb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-zwvijwe\" data-id=\"zwvijwe\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cictybc elementor-widget elementor-widget-heading\" data-id=\"cictybc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">NANO4DERM<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ytqhswr elementor-widget elementor-widget-text-editor\" data-id=\"ytqhswr\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5>Nanocapsules containing active substances for the topical treatment of dermatological diseases<\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-jxszbaa elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"jxszbaa\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fhqmqhj\" data-id=\"fhqmqhj\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-xepvqrx elementor-widget elementor-widget-text-editor\" data-id=\"xepvqrx\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>ABSTRACT<\/strong><\/p><p style=\"text-align: justify;\">The research project Nano4Derm will focus on the development of innovative formulations containing nanoencapsulated active ingredients for the treatment of inflammatory skin diseases, such as Acne and Psoriasis. This project will lead to the development of two types of nanocapsules containing active ingredients aiming to address current unmet needs and challenges, such as antimicrobial resistance, and will provide improved topical treatments in terms of side effects, instability of active ingredients, and skin penetration.<\/p><p style=\"text-align: justify;\">The project is a collaboration between Almirall, S.A. and the Institute of Material Science of Barcelona from CSIC (ICMAB-CSIC), and LEITAT, focused in nanomedicine applied to treat dermatological diseases. Within the framework of this research project, new innovative formulations containing nanoencapsulated active ingredients will be developed for the topical treatment of inflammatory skin conditions, such as Acne and Psoriasis.<\/p><p style=\"text-align: justify;\">Nano4Derm involves the development and physico-chemical and biological characterisation of nanocapsules containing active ingredients, and the generation of scalable formulation prototypes for manufacturing nanoformulations suitable for clinical trials. These innovative formulations will address current unmet needs and challenges, such as antimicrobial resistance, and provide improved topical treatments for Acne and Psoriasis, in terms of side effects, instability of active ingredients, and skin penetration.<\/p><p style=\"text-align: justify;\">Under the terms of the agreement, ICMAB-CSIC and LEITAT will be in charge of developing the different prototypes of nanocapsules containing the active ingredients while Almirall will be responsible for the development of formulations containing the encapsulated actives. Furthermore, Almirall and LEITAT will evaluate in preclinical studies both the new nanocapsules and formulations in order to select the best solution to address the unmet medical needs in the topical treatment of Acne and Psoriasis.<\/p><p style=\"text-align: justify;\">This agreement will lead to the development of two types of nanocapsules: Quatsomes and Polymeric Nanocapsules. Quatsomes are lipid nanoparticles with higher colloidal stability than liposomes, which favors the production of high quality, pharmaceutical formulations. They are obtained from the DELOS-SUSP, a technology developed by researchers from the Nanomol group (ICMAB-CSIC) based on the use of supercritical fluids such as CO2. This technology has advantages over other manufacturing methodologies in terms of homogeneity and scalability, as it replaces the use of organic solvents by green solvents. Polymeric Nanocapsules are developed by the Leitat Technology Center, and provide versatility to the project as they can be designed with different drug release profiles depending on the needs being addressed.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-kdkiyce elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"kdkiyce\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-xmkbjno\" data-id=\"xmkbjno\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-walvbul elementor-widget elementor-widget-text-editor\" data-id=\"walvbul\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Project Budget:<\/strong> 1&#8217;021&#8217;575,32 \u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-tgvmvuj\" data-id=\"tgvmvuj\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dvnbqan elementor-widget elementor-widget-text-editor\" data-id=\"dvnbqan\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Financial Framework:<\/strong> RETOS COLABORACI\u00d3N<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-molsfwd elementor-widget elementor-widget-text-editor\" data-id=\"molsfwd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contract number:<\/strong> RTC-2016-4567-1<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-ygptdup\" data-id=\"ygptdup\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-tdklpxx elementor-widget elementor-widget-text-editor\" data-id=\"tdklpxx\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Start Date:<\/strong> 01\/10\/2016<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-jlrlgbn elementor-widget elementor-widget-text-editor\" data-id=\"jlrlgbn\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>End Date:<\/strong> 31\/12\/2018<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-tlvrkie elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"tlvrkie\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-gydshax\" data-id=\"gydshax\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eolbles elementor-widget elementor-widget-text-editor\" data-id=\"eolbles\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Partners:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-lobpclz elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"lobpclz\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fbhtjwb\" data-id=\"fbhtjwb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-jhlfiee elementor-widget elementor-widget-image-gallery\" data-id=\"jhlfiee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-gallery.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-gallery\">\n\t\t\t<div id='gallery-1' class='gallery galleryid-59980 gallery-columns-4 gallery-size-blog-list-post-size'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"150\" height=\"150\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/Logo-Almirall.jpg\" class=\"attachment-blog-list-post-size size-blog-list-post-size\" alt=\"\" aria-describedby=\"gallery-1-47733\" decoding=\"async\" \/>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-47733'>\n\t\t\t\tCoordinator\n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"200\" height=\"200\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/ICMAB-square.png\" class=\"attachment-blog-list-post-size size-blog-list-post-size\" alt=\"\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/ICMAB-square.png 200w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/ICMAB-square-150x150.png 150w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon portrait'>\n\t\t\t\t<img fetchpriority=\"high\" width=\"400\" height=\"420\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/LEITAT-400x420-1.png\" class=\"attachment-blog-list-post-size size-blog-list-post-size\" alt=\"\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/LEITAT-400x420-1.png 400w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/LEITAT-400x420-1-286x300.png 286w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-nzunqer elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"nzunqer\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-atoevme\" data-id=\"atoevme\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-xptbyoy elementor-widget elementor-widget-text-editor\" data-id=\"xptbyoy\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contact Manager:<\/strong> <a href=\"mailto:snieva@leitat.org\">S. Nieva<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-oytmhgp elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"oytmhgp\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-dndfkso\" data-id=\"dndfkso\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-pvmkqpd elementor-widget elementor-widget-image\" data-id=\"pvmkqpd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"155\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg\" class=\"attachment-large size-large wp-image-51091\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-300x58.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-768x149.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1536x298.jpg 1536w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41886d9 elementor-widget elementor-widget-image\" data-id=\"41886d9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"535\" height=\"142\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1.png\" class=\"attachment-large size-large wp-image-55247\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1.png 535w, https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1-300x80.png 300w\" sizes=\"(max-width: 535px) 100vw, 535px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-swaijps\" data-id=\"swaijps\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-sudqqlb elementor-widget elementor-widget-text-editor\" data-id=\"sudqqlb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Financiado por: FEDER\/Ministerio de Ciencia,Innovaci\u00f3n y Universidades \u2013 Agencia Estatal de Investigaci\u00f3n\/_Proyecto RTC-2016-4567-1<\/p><p>Objetivo Tem\u00e1tico del Programa Operativo: Promover el desarrollo tecnol\u00f3gico, la innovaci\u00f3n y una investigaci\u00f3n de calidad.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>NANO4DERM Nanocapsules containing active substances for the topical treatment of dermatological diseases ABSTRACT The research project Nano4Derm will focus on the development of innovative formulations containing nanoencapsulated active ingredients for the treatment of inflammatory skin diseases, such as Acne and Psoriasis. This project will lead to the development of two types of nanocapsules containing active [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":47173,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[142],"tags":[112],"class_list":["post-59980","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-technologies-en","tag-projects"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>NANO4DERM - Leitat Technological Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NANO4DERM - Leitat Technological Center\" \/>\n<meta property=\"og:description\" content=\"NANO4DERM Nanocapsules containing active substances for the topical treatment of dermatological diseases ABSTRACT The research project Nano4Derm will focus on the development of innovative formulations containing nanoencapsulated active ingredients for the treatment of inflammatory skin diseases, such as Acne and Psoriasis. 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