{"id":74713,"date":"2025-11-11T10:43:05","date_gmt":"2025-11-11T10:43:05","guid":{"rendered":"https:\/\/leitat.org\/?p=74713"},"modified":"2025-11-11T11:03:18","modified_gmt":"2025-11-11T11:03:18","slug":"the-efgr-lyac-project-consortium-meets-at-the-crg-facilities","status":"publish","type":"post","link":"https:\/\/leitat.org\/en\/blog\/the-efgr-lyac-project-consortium-meets-at-the-crg-facilities\/","title":{"rendered":"The EGFR-LYTAC project consortium meets at the CRG facilities"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"74713\" class=\"elementor elementor-74713 elementor-74695\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8b4f37f e-flex e-con-boxed e-con e-parent\" data-id=\"8b4f37f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e4c0cdb elementor-widget elementor-widget-text-editor\" data-id=\"e4c0cdb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" tabindex=\"-1\" data-turn-id=\"a43414cd-41fa-437f-a304-b2845c9f8ef8\" data-testid=\"conversation-turn-8\" data-scroll-anchor=\"true\" data-turn=\"assistant\"><div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\"><div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\" tabindex=\"-1\"><div class=\"flex max-w-full flex-col grow\"><div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"7e776f21-fdd3-45d4-9f97-3e000c6f5f12\" data-message-model-slug=\"gpt-5-mini\"><div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\"><div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\"><p data-start=\"0\" data-end=\"301\">On October 10, the EGFR-LYTAC project consortium met in person at the facilities of the Center for Genomic Regulation (CRG), one of the project partners. During the meeting, the participants reviewed the status of each task and defined the next steps to ensure the proper development of the project.<\/p><p data-start=\"303\" data-end=\"625\">The EGFR-LYTAC project, funded under the PCPP 2023 call, aims to develop a new therapy to combat a specific type of hard-to-treat lung cancer. To achieve this, specific antibodies are used that act as \u201csmart messengers\u201d: they target the EGFR protein, which helps cancer cells grow, and eliminate it from within the cell.<\/p><p data-start=\"627\" data-end=\"823\">This approach combines two cutting-edge technologies:<\/p><ul><li data-start=\"627\" data-end=\"823\"><strong data-start=\"685\" data-end=\"698\">mAbLYTACs<\/strong>, which enable the cell to destroy the target protein.<\/li><li data-start=\"627\" data-end=\"823\"><strong data-start=\"757\" data-end=\"764\">ADC<\/strong>, which delivers a toxic drug directly to the tumor cell.<\/li><\/ul><p>\u00a0<\/p><p data-start=\"825\" data-end=\"967\">The combination of these strategies could be effective even in cases where other treatments fail, such as tumors resistant due to mutations.<\/p><p data-start=\"969\" data-end=\"1126\">At Leitat, leaders of Task 6, we presented the progress in obtaining antibodies, a key element for the development of this innovative therapeutic strategy.<\/p><p data-start=\"969\" data-end=\"1126\">\u00a0<\/p><p data-start=\"1128\" data-end=\"1165\" data-is-last-node=\"\" data-is-only-node=\"\"><em>Project CPP2023-010665 funded by:<\/em><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/article>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6757601 e-flex e-con-boxed e-con e-parent\" data-id=\"6757601\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8c57841 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"8c57841\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"543\" height=\"105\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2025\/11\/egfr-lytac_logos.jpg\" class=\"attachment-large size-large wp-image-74702\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2025\/11\/egfr-lytac_logos.jpg 543w, https:\/\/leitat.org\/wp-content\/uploads\/2025\/11\/egfr-lytac_logos-300x58.jpg 300w\" sizes=\"(max-width: 543px) 100vw, 543px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>On October 10, the EGFR-LYTAC project consortium met in person at the facilities of the Center for Genomic Regulation (CRG), one of the project partners. During the meeting, the participants reviewed the status of each task and defined the next steps to ensure the proper development of the project. The EGFR-LYTAC project, funded under the [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":74698,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[149,142],"tags":[208],"class_list":["post-74713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aei-en","category-health-technologies-en","tag-blog-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The EGFR-LYTAC project consortium meets at the CRG facilities - Leitat Technological Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The EGFR-LYTAC project consortium meets at the CRG facilities - Leitat Technological Center\" \/>\n<meta property=\"og:description\" content=\"On October 10, the EGFR-LYTAC project consortium met in person at the facilities of the Center for Genomic Regulation (CRG), one of the project partners. 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