{"id":75967,"date":"2026-01-12T11:19:59","date_gmt":"2026-01-12T11:19:59","guid":{"rendered":"https:\/\/leitat.org\/?p=75967"},"modified":"2026-01-12T11:25:28","modified_gmt":"2026-01-12T11:25:28","slug":"hpk1-inhib","status":"publish","type":"post","link":"https:\/\/leitat.org\/es\/blog\/hpk1-inhib\/","title":{"rendered":"HPK1-INHIB"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"75967\" class=\"elementor elementor-75967\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-73935fd e-flex e-con-boxed e-con e-parent\" data-id=\"73935fd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d68ecbd elementor-widget elementor-widget-text-editor\" data-id=\"d68ecbd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em><span class=\"TextRun SCXW27446755 BCX8\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW27446755 BCX8\">Descubrimiento y desarrollo precl\u00ednico de nuevos compuestos como inhibidores de HPK1 para el tratamiento del c\u00e1ncer<\/span><\/span><span class=\"EOP SCXW27446755 BCX8\" data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;469777462&quot;:[3615],&quot;469777927&quot;:[0],&quot;469777928&quot;:[1]}\">\u00a0<\/span><\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-06c088d e-flex e-con-boxed e-con e-parent\" data-id=\"06c088d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f182c8 elementor-widget elementor-widget-text-editor\" data-id=\"7f182c8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Abstract:<\/strong><\/p><p><span data-contrast=\"auto\">El objetivo general del proyecto es descubrir y desarrollar a nivel precl\u00ednico nuevos inhibidores de HPK1, con potencial terap\u00e9utico en oncolog\u00eda. Para ello, se abordar\u00e1n etapas clave como el dise\u00f1o, s\u00edntesis y optimizaci\u00f3n de compuestos, evaluaci\u00f3n de propiedades ADME, estudios de eficacia in vitro e in vivo, escalado de s\u00edntesis y solicitud de patentes.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;469777462&quot;:[3615],&quot;469777927&quot;:[0],&quot;469777928&quot;:[1]}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">El proyecto ser\u00e1 ejecutado por un consorcio formado por Medchemfarma, Leitat y la Universidad de Santiago de Compostela (USC), combinando experiencia en qu\u00edmica m\u00e9dica, farmacolog\u00eda y descubrimiento temprano de f\u00e1rmacos. Tambi\u00e9n se contar\u00e1 con la subcontrataci\u00f3n de servicios especializados para etapas concretas del desarrollo.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;469777462&quot;:[3615],&quot;469777927&quot;:[0],&quot;469777928&quot;:[1]}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Este proyecto se alinea con los objetivos del Plan de Recuperaci\u00f3n, Transformaci\u00f3n y Resiliencia (PRTR), reforzando la I+D en salud. Un Comit\u00e9 de Direcci\u00f3n T\u00e9cnica coordinar\u00e1 el trabajo, asegurando el cumplimiento de objetivos, la protecci\u00f3n de resultados y su adecuada difusi\u00f3n.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;469777462&quot;:[3615],&quot;469777927&quot;:[0],&quot;469777928&quot;:[1]}\">\u00a0<\/span><\/p><p>\u00a0<\/p><p><strong>Rol de Leitat en el proyecto:<\/strong><\/p><p>Leitat actuar\u00e1 como socio beneficiario en el proyecto HPK1-INHIB.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-181444b e-flex e-con-boxed e-con e-parent\" data-id=\"181444b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-09b0ccd e-con-full e-flex e-con e-child\" data-id=\"09b0ccd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0eaab40 elementor-widget elementor-widget-text-editor\" data-id=\"0eaab40\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Presupuesto del proyecto:<\/strong> 896.221,99\u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8140e92 e-con-full e-flex e-con e-child\" data-id=\"8140e92\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-278b52e elementor-widget elementor-widget-text-editor\" data-id=\"278b52e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Marco financiero:<\/strong> <span class=\"TextRun SCXW77155954 BCX8\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW77155954 BCX8\">Proyectos de colaboraci\u00f3n p\u00fablico-privada 2022<\/span><\/span><span class=\"EOP SCXW77155954 BCX8\" data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a682b4 e-con-full e-flex e-con e-child\" data-id=\"2a682b4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-15addf4 elementor-widget elementor-widget-text-editor\" data-id=\"15addf4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Fecha de inicio:\u00a0 \u00a0\u00a0<\/strong> 01\/03\/2023<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1f1b4f6 e-con-full e-flex e-con e-child\" data-id=\"1f1b4f6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1abfb99 elementor-widget elementor-widget-text-editor\" data-id=\"1abfb99\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Presupuesto de Leitat:<\/strong> 200.396,63\u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d66261c e-con-full e-flex e-con e-child\" data-id=\"d66261c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a2b3d0 elementor-widget elementor-widget-text-editor\" data-id=\"1a2b3d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>N\u00famero de contrato:<\/strong> <span class=\"TextRun SCXW80534510 BCX8\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW80534510 BCX8\">CPP2022-009716<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ca06880 e-con-full e-flex e-con e-child\" data-id=\"ca06880\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ce05b25 elementor-widget elementor-widget-text-editor\" data-id=\"ce05b25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Fecha de finalizaci\u00f3n:<\/strong> 28\/02\/2026<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d78e34b e-flex e-con-boxed e-con e-parent\" data-id=\"d78e34b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9fe5c91 elementor-widget elementor-widget-text-editor\" data-id=\"9fe5c91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Socios:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2bd1ff2 e-flex e-con-boxed e-con e-parent\" data-id=\"2bd1ff2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-80e6797 elementor-widget elementor-widget-image\" data-id=\"80e6797\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"466\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2026\/01\/partners-HPK1-INHIB-1024x597.png\" class=\"attachment-large size-large wp-image-75972\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2026\/01\/partners-HPK1-INHIB-1024x597.png 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2026\/01\/partners-HPK1-INHIB-300x175.png 300w, https:\/\/leitat.org\/wp-content\/uploads\/2026\/01\/partners-HPK1-INHIB-768x448.png 768w, https:\/\/leitat.org\/wp-content\/uploads\/2026\/01\/partners-HPK1-INHIB.png 1200w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-673ac2d e-flex e-con-boxed e-con e-parent\" data-id=\"673ac2d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b8d4cf elementor-widget elementor-widget-text-editor\" data-id=\"3b8d4cf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW197214340 BCX8\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW197214340 BCX8\">Proyecto\u00a0<\/span><span class=\"NormalTextRun SCXW197214340 BCX8\">CPP2022-009716<\/span><span class=\"NormalTextRun SCXW197214340 BCX8\">\u00a0<\/span><span class=\"NormalTextRun SCXW197214340 BCX8\">financiado por:<\/span><span class=\"NormalTextRun SCXW197214340 BCX8\">\u202f<\/span><\/span><span class=\"EOP SCXW197214340 BCX8\" data-ccp-props=\"{&quot;335551550&quot;:2,&quot;335551620&quot;:2}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d9f5997 e-flex e-con-boxed e-con e-parent\" data-id=\"d9f5997\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-16630cd elementor-widget elementor-widget-image\" data-id=\"16630cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"668\" height=\"156\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2025\/08\/Imagen1.jpg\" class=\"attachment-large size-large wp-image-72542\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2025\/08\/Imagen1.jpg 668w, https:\/\/leitat.org\/wp-content\/uploads\/2025\/08\/Imagen1-300x70.jpg 300w\" sizes=\"(max-width: 668px) 100vw, 668px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Descubrimiento y desarrollo precl\u00ednico de nuevos compuestos como inhibidores de HPK1 para el tratamiento del c\u00e1ncer\u00a0 Abstract: El objetivo general del proyecto es descubrir y desarrollar a nivel precl\u00ednico nuevos inhibidores de HPK1, con potencial terap\u00e9utico en oncolog\u00eda. Para ello, se abordar\u00e1n etapas clave como el dise\u00f1o, s\u00edntesis y optimizaci\u00f3n de compuestos, evaluaci\u00f3n de propiedades [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":75968,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[13,14],"tags":[15],"class_list":["post-75967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aei","category-health-technologies","tag-proyectos"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HPK1-INHIB - Leitat Technological Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HPK1-INHIB - Leitat Technological Center\" \/>\n<meta property=\"og:description\" content=\"Descubrimiento y desarrollo precl\u00ednico de nuevos compuestos como inhibidores de HPK1 para el tratamiento del c\u00e1ncer\u00a0 Abstract: El objetivo general del proyecto es descubrir y desarrollar a nivel precl\u00ednico nuevos inhibidores de HPK1, con potencial terap\u00e9utico en oncolog\u00eda. 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