{"id":8042,"date":"2014-07-27T09:20:35","date_gmt":"2014-07-27T07:20:35","guid":{"rendered":"http:\/\/dev-leitat-projects-blog.pantheonsite.io\/?p=8042"},"modified":"2025-02-24T20:33:40","modified_gmt":"2025-02-24T20:33:40","slug":"metastasis","status":"publish","type":"post","link":"https:\/\/leitat.org\/es\/blog\/metastasis\/","title":{"rendered":"METASTASIS"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"8042\" class=\"elementor elementor-8042\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-avvriqf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"avvriqf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-shdemfd\" data-id=\"shdemfd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-tndhnny elementor-widget elementor-widget-heading\" data-id=\"tndhnny\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">METASTASIS<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-xslpjaz elementor-widget elementor-widget-text-editor\" data-id=\"xslpjaz\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5>Anti-tumor and anti-metastasis activity of monoclonal antibodies in animal models of human cancers<\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-blpkgfo elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"blpkgfo\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ycuwllr\" data-id=\"ycuwllr\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-yrqagth elementor-widget elementor-widget-text-editor\" data-id=\"yrqagth\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>ABSTRACT<\/strong><\/p><p style=\"text-align: justify;\"><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"La efectividad limitada de los tratamientos aprobados, as\u00ed como las evidencias de sus resistencias y toxicidades, enfatizan la necesidad del desarrollo de nuevos anticuerpos monoclonales terap\u00e9uticos para mejorar la eficacia en los tratamientos de met\u00e1stasis de tumores en mama o p\u00e1ncreas, o en tumores hematol\u00f3gicos (leucemias\">The limited effectiveness of approved treatments, as well as evidence of their resistance and toxicities, emphasize the need for the development of new therapeutic monoclonal antibodies to improve the efficacy of metastases in tumors in the breast or pancreas, or in hematological tumors (leukemias <\/span><span title=\"y linfomas). \">And lymphomas).<\/span><\/span><\/p><p style=\"text-align: justify;\"><span title=\"Durante la anualidad 2016 de este proyecto se ha estado trabajando en los siguientes objetivos claramente definidos y diferenciados: \u00a0\u00a0\u00a0\u00a0\">The METASTASIS project works on the following clearly defined and differentiated objectives:<\/span><\/p><ul style=\"text-align: justify;\"><li><ul><li><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"FIBHULP ha constatado en experimentos in vitro que el anticuerpo monoclonal contra CCR7 es eficaz en un gran n\u00famero de leucemias y linfomas. \u00a0\u00a0\u00a0\u00a0\">FIBHULP has found in in vitro experiments that the monoclonal antibody against CCR7 is effective in a large number of leukemias and lymphomas.<\/span><\/span><\/li><li><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"IMMED ha empezado el desarrollo de modelos animales de aquellas enfermedades en las que FIBHULP ha demostrado eficacia del anticuerpo monoclonal contra CCR7. \u00a0\u00a0\u00a0\u00a0\">IMMED has begun the development of animal models of those diseases in which FIBHULP has demonstrated efficacy of the monoclonal antibody against CCR7.<\/span><\/span><\/li><li><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"Leitat ha llevado a cabo la selecci\u00f3n de l\u00edneas tumorales para realizar los estudios de eficacia con los anticuerpos monoclonales contra S100A4, S100P y S100A7 as\u00ed como la producci\u00f3n de la cantidad necesaria de anticuerpo contra las tres prote\u00ednas, paso previo a los estudios funcionales in vitro (\">LEITAT has performed the selection of tumor lines to perform efficacy studies with the monoclonal antibodies against S100A4, S100P and S100A7 as well as the production of the necessary amount of antibody against the three proteins prior to the in vitro functional studies (o<\/span><span title=\"en marcha) e in vivo. \">n the fly) and in vivo. <\/span><\/span><\/li><\/ul><\/li><\/ul><p style=\"text-align: justify;\"><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"El consorcio que lo est\u00e1 llevando a cabo est\u00e1 formado por una empresa, Immunological and Medicinal Products (IMMED) y dos centros de reconocido prestigio internacional: la Fundaci\u00f3n para la Investigaci\u00f3n Biom\u00e9dica del Hospital Universitario de la Princesa (FIBHULP) y el centro tecnol\u00f3gico Leitat.\">The consortium is carrying out a company, Immunological and Medicinal Products (IMMED) and two centers of recognized international prestige: the Foundation for Biomedical Research of the Hospital Universitario de la Princesa (FIBHULP) and the Leitat technology center. <\/span><span title=\"IMMED es una empresa con amplia experiencia en el desarrollo de terapias y m\u00e9todos de diagn\u00f3stico molecular para oncolog\u00eda y enfermedades inflamatorias y autoinmunes.\">IMMED is a company with extensive experience in the development of molecular diagnostic methods and therapies for oncology and inflammatory and autoimmune diseases. <\/span><span title=\"IMMED participar\u00e1 en la validaci\u00f3n pre-cl\u00ednica y funcional de los anticuerpos leads.\">IMMED will participate in pre-clinical and functional validation of antibody leads. <\/span><span title=\"El centro FIBHULP participar\u00e1 en los ensayos in vitro de la uni\u00f3n de los anticuerpos y Leitat participar\u00e1 en determinar la eficacia de la actividad de los anticuerpos en l\u00edneas celulares y la determinaci\u00f3n de la actividad antiangiog\u00e9nica y antimetast\u00e1sica en modelos animales in vivo.\">The FIBHULP center will participate in the in vitro assays of antibody binding and Leitat will participate in determining the efficacy of antibody activity in cell lines and the determination of antiangiogenic and antimetastase activity in animal models in vivo. <\/span><span title=\"Se espera que esta estrategia mejore la eficacia de los tratamientos de met\u00e1stasis de tumores en mama o p\u00e1ncreas. \">This strategy is expected to improve the efficacy of metastatic treatments for tumors in the breast or pancreas.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-sjjghuu elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"sjjghuu\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-woqpybl\" data-id=\"woqpybl\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-njdhopc elementor-widget elementor-widget-text-editor\" data-id=\"njdhopc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Project Budget:<\/strong> 573&#8217;680,20 \u20ac<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-ydkkjtw\" data-id=\"ydkkjtw\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ybjavio elementor-widget elementor-widget-text-editor\" data-id=\"ybjavio\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Financial Framework:<\/strong> RETOS COLABORACI\u00d3N<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ftdgjmf elementor-widget elementor-widget-text-editor\" data-id=\"ftdgjmf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contract number:<\/strong> RTC-2015-3318-1<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-qzqxazv\" data-id=\"qzqxazv\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-qphayga elementor-widget elementor-widget-text-editor\" data-id=\"qphayga\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Start Date:<\/strong> 01\/07\/2015<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-lrzktrw elementor-widget elementor-widget-text-editor\" data-id=\"lrzktrw\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>End Date:<\/strong> 31\/12\/2017<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-rhvpvxz elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"rhvpvxz\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ezzjgou\" data-id=\"ezzjgou\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cofajvr elementor-widget elementor-widget-text-editor\" data-id=\"cofajvr\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Partners:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-pycwdof elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"pycwdof\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ddzuafw\" data-id=\"ddzuafw\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-exzkznr elementor-widget elementor-widget-image-gallery\" data-id=\"exzkznr\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image-gallery.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-image-gallery\">\n\t\t\t<div id='gallery-1' class='gallery galleryid-8042 gallery-columns-4 gallery-size-excerpt-thumbnail'><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img fetchpriority=\"high\" width=\"2291\" height=\"624\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED.jpg\" class=\"attachment-excerpt-thumbnail size-excerpt-thumbnail\" alt=\"\" aria-describedby=\"gallery-1-9149\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED.jpg 2291w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED-300x82.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED-768x209.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED-1024x279.jpg 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED-1536x418.jpg 1536w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/IMMED-2048x558.jpg 2048w\" sizes=\"(max-width: 2291px) 100vw, 2291px\" \/>\n\t\t\t<\/div>\n\t\t\t\t<figcaption class='wp-caption-text gallery-caption' id='gallery-1-9149'>\n\t\t\t\tCoordinator\n\t\t\t\t<\/figcaption><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"340\" height=\"200\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/logo-retina-cab_iis-laprincesa_100x175px.png\" class=\"attachment-excerpt-thumbnail size-excerpt-thumbnail\" alt=\"\" decoding=\"async\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/logo-retina-cab_iis-laprincesa_100x175px.png 340w, https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/logo-retina-cab_iis-laprincesa_100x175px-300x176.png 300w\" sizes=\"(max-width: 340px) 100vw, 340px\" \/>\n\t\t\t<\/div><\/figure><figure class='gallery-item'>\n\t\t\t<div class='gallery-icon landscape'>\n\t\t\t\t<img width=\"200\" height=\"76\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2017\/08\/Leitat_ppt-200.png\" class=\"attachment-excerpt-thumbnail size-excerpt-thumbnail\" alt=\"\" decoding=\"async\" \/>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fgbrqvw elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fgbrqvw\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-gbswdkh\" data-id=\"gbswdkh\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-pdvzsdp elementor-widget elementor-widget-text-editor\" data-id=\"pdvzsdp\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contact Manager:<\/strong> <a href=\"mailto:snieva@leitat.org\">S. Nieva<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-vysxdcg elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"vysxdcg\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-cpmdfoa\" data-id=\"cpmdfoa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-vpqfyag elementor-widget elementor-widget-image\" data-id=\"vpqfyag\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"155\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg\" class=\"attachment-large size-large wp-image-14328\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1024x199.jpg 1024w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-300x58.jpg 300w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-768x149.jpg 768w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI-1536x298.jpg 1536w, https:\/\/leitat.org\/wp-content\/uploads\/2019\/04\/MCIU_Gob_Web_AEI.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cebf7c0 elementor-widget elementor-widget-image\" data-id=\"cebf7c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"535\" height=\"142\" src=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1.png\" class=\"attachment-large size-large wp-image-40410\" alt=\"\" srcset=\"https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1.png 535w, https:\/\/leitat.org\/wp-content\/uploads\/2016\/10\/LOGO_FEDER_es-670x300-1-300x80.png 300w\" sizes=\"(max-width: 535px) 100vw, 535px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-wjvnqdl\" data-id=\"wjvnqdl\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-qhdednq elementor-widget elementor-widget-text-editor\" data-id=\"qhdednq\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Financiado por: FEDER\/Ministerio de Ciencia,Innovaci\u00f3n y Universidades \u2013 Agencia Estatal de Investigaci\u00f3n\/_Proyecto RTC-2015-3318-1<\/p><p>Objetivo Tem\u00e1tico del Programa Operativo: Promover el desarrollo tecnol\u00f3gico, la innovaci\u00f3n y una investigaci\u00f3n de calidad.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>METASTASIS Anti-tumor and anti-metastasis activity of monoclonal antibodies in animal models of human cancers ABSTRACT The limited effectiveness of approved treatments, as well as evidence of their resistance and toxicities, emphasize the need for the development of new therapeutic monoclonal antibodies to improve the efficacy of metastases in tumors in the breast or pancreas, or [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8043,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[14],"tags":[15],"class_list":["post-8042","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-technologies","tag-proyectos"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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